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Prospectio + Clay

Prospectio handles the outreach. Clay handles everything that happens either side of it. Together they let you trigger campaigns from any signal and send the results anywhere.

Paul CassidyBy Paul Cassidy, founder of Prospectio.ai. Ex Google, Salesforce and Twilio sales leader. Updated 5 September 2026.
In short: use Clay to start Prospectio campaigns from signals in any other tool, and to route replies, meetings and outcomes wherever you need them. Connect with an API key and a POST request. No Prospectio app in Clay yet, so it is built with Clay's HTTP API column.

Why wire it up

Most teams have the signal that should start an outreach campaign sitting in a different system to the one that sends it. Someone fills in a form, a company appears in an intent feed, a target account hires for a role, a trial signup goes cold. Each of those is a reason to reach out, and in most companies each of them gets noticed a week late by a human scrolling a dashboard.

Clay closes that gap. The signal fires, the prospect enters the right Prospectio campaign, the ICP filter checks they are worth messaging, and the sequence starts the same day.

What you can trigger

  • Add a prospect to a specific campaign, with any custom fields you want available for personalisation
  • Pause or resume a prospect’s sequence, for example when they open a support ticket or a deal moves stage
  • Update a prospect’s details mid-sequence
  • Remove a prospect entirely, which matters for suppression lists

What Prospectio sends out

  • Connection request sent, and accepted
  • Message or voice note delivered
  • Reply received, with the text and the responder’s classification (interested, question, objection, not now, not interested)
  • Meeting booked, with the time and the calendar link
  • Prospect skipped by the ICP filter, with the reason, which is useful for auditing your targeting

Workflows worth building

Website visitor to campaign. A deanonymisation tool identifies a company, Clay looks up the right contact, Prospectio qualifies and starts a sequence.

Form fill to instant follow-up. Someone downloads something, Clay adds them to a nurture campaign that opens with a voice note rather than an autoresponder email.

Job ad signal to outreach. A monitoring tool spots a target account hiring for a role that signals need, and the campaign starts automatically.

Reply to Slack. Every positive reply posts into a channel so the team sees momentum, which does more for morale than a weekly report.

Meeting booked to CRM and calendar. Belt and braces alongside the native CRM sync.

Setting it up

Clay has no native Prospectio integration yet, so you connect using Clay’s HTTP API enrichment.

  1. In Prospectio, go to Settings → Integrations and generate an API key
  2. In Clay, add an HTTP API column to your table
  3. Set the method to POST and the body to JSON
  4. Add a header called X-API-KEY with your key
  5. Map profileUrl from your LinkedIn URL column, and add your campaignUuid and linkedinAccountUuid
  6. Run it on a single row before you run the table

Your campaign UUID is on the campaigns page, under the three dots and View details. Your LinkedIn account UUID is on the accounts page, under the three dots and Copy.

Clay’s HTTP API column consumes credits per row, so test on one row rather than a full table.

A caution

Automated triggers make it easy to accidentally message someone twice, or to message an existing customer. Keep a suppression list, and route everything through the ICP filter rather than straight into a sequence. The filter skipping a prospect is a feature, not an error in your automation.

Frequently asked questions

What can I trigger with Clay?

Adding a prospect to a campaign, pausing or resuming a sequence, and updating an existing prospect's details. The most common pattern is a signal in another tool starting a Prospectio campaign automatically.

What events does Prospectio send out?

Connection accepted, message sent, reply received with the message text and its classification, meeting booked, and prospect skipped by the ICP filter with the reason.

Do I need to write code?

No, but it is not a one-click connection either. There is no Prospectio app in Clay yet, so you wire it up with Clay's HTTP API column: a POST request, an X-API-KEY header, and three fields in the body. Ten minutes if you have done it before, half an hour if you have not.

Want us to run it for you?

Prospectio Pipeline is our done-for-you LinkedIn and email outreach service, from €1,500 a month. It starts with a 30-minute scoping call on your offer, your buyers and your targets.